A steroidal derivative from Trigonella foenum graecum L. that induces apoptosis in vitro and in vivo
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چکیده
منابع مشابه
In Vitro Anti-plasmodial activity of Trigonella foenum–graecum L.
Developing countries, where malaria is one of the most prevalent diseases, still rely on traditional medicine as a source for the treatment of this disease. For the present study, Trigonella foenum-graecum L. (fenugreek) were collected from Coimbatore, Tamilnadu, India. The test plant has been used in India by traditional healers for the treatment of fever as well as other diseases. The active ...
متن کاملIn vitro estrogenic activities of fenugreek Trigonella foenum graecum seeds.
BACKGROUND & OBJECTIVES Trigonella foenum graecum commonly known as fenugreek, has been widely cultivated in Asia, Africa and Mediterranean countries for the edible and medicinal values of its seeds. Earlier reports show that fenugreek seeds provide a mastogenic effect resulting in enhanced breast size. However, very little is known about its estrogenic effect. The present study investigated th...
متن کاملDetermination of Steroidal Saponins and Fixed Oil Content in Fenugreek (Trigonella foenum-graecum) Genotypes
Trigonella foenum-graecum, commonly called fenugreek, is a leguminous plant native to many Asian, Middle Eastern and European countries. Fenugreek oil is very effective in digestion. Identification of fenugreek genotype rich in saponins and fixed oil will be useful for pharmaceutical industries. In the present study, steroidal saponin and fixed oil content was analysed in 46 diverse fenugreek g...
متن کاملEffects of Saponin from Trigonella Foenum-Graecum Seeds on Dyslipidemia
Background Saponins identified from fenugreek (Trigonella foenum-graecum) seeds are reported effective on dyslipidemia. However, the definite mechanism is still not elucidated systematically. In this study, we evaluate the effects of saponin extract on cholesterol absorption, metabolism, synthesis, and reverse cholesterol transport in vivo. Methods Saponin extract was prepared according to a ...
متن کاملIn vitro studies on antiradical and antioxidant activities of fenugreek (Trigonella foenum graecum) seeds
An extract of fenugreek (Trigonella foenum graecum) seeds was isolated and evaluated for antioxidant activity using various in vitro assay systems. The seed extract exhibited scavenging of hydroxyl radicals ( OH) and inhibition of hydrogen peroxide-induced lipid peroxidation in rat liver mitochondria. The OH scavenging activity of the extract was evaluated by pulse radiolysis and the deoxyribos...
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ژورنال
عنوان ژورنال: Journal of Food and Drug Analysis
سال: 2019
ISSN: 1021-9498
DOI: 10.1016/j.jfda.2018.05.001